Research of CBD and Cancer

Cancer includes a large group of diseases that cause unregulated and rapid cell growth. The unregulated growth allows cancer cells to penetrate healthy tissue and destroy it. Cancer usually starts in one part of the body but it can spread through the bloodstream and lymphatic system. More than 200 types of cancer affect people and everyone experiences different symptoms, depending on where the cancer is located.

Brain cancer
Breast cancer
Lung cancer
Prostate cancer
Blood cancer (Leukaemia)
Oral cancer
Liver cancer
Pancreatic cancer

Brain cancer

Neuroprotection by Δ9-Tetrahydrocannabinol, the Main Active Compound in Marijuana, against Ouabain-Induced In Vivo Excitotoxicity (2001)

Antitumor Effects of Cannabidiol, a Nonpsychoactive Cannabinoid, on Human Glioma Cell Lines (2003)

A pilot clinical study of Δ9-tetrahydrocannabinol in patients with recurrent glioblastoma multiforme (2006)

A Combined Preclinical Therapy of Cannabinoids and Temozolomide against Glioma (2011)

Breast cancer

Anti-tumor activity of plant cannabinoids with emphasis on the effect of cannabidiol on human breast carcinoma (2006)

Pathways mediating the effects of cannabidiol on the reduction of breast cancer cell proliferation, invasion, and metastasis (2010)

Cannabinoids reduce ErbB2-driven breast cancer progression through Akt inhibition (2010)

The endogenous cannabinoid anandamide inhibits human breast cancer cell proliferation (1998)

Lung cancer

Δ9-Tetrahydrocannabinol inhibits epithelial growth factor-induced lung cancer cell migration in vitro as well as its growth and metastasis in vivo (2008)

Cannabidiol inhibits lung cancer cell invasion and metastasis via intercellular adhesion molecule-1 (2011)

Cannabinoid receptors, CB1 and CB2, as novel targets for inhibition of non-small cell lung cancer growth and metastasis (2011)

Prostate cancer

Anti-proliferative and apoptotic effects of anandamide in human prostatic cancer cell lines: implication of epidermal growth factor receptor down-regulation and ceramide production (2003)

The role of cannabinoids in prostate cancer: Basic science perspective and potential clinical applications (2012)

Non-THC cannabinoids inhibit prostate carcinoma growth in vitro and in vivo: pro-apoptotic effects and underlying mechanisms (2013)

Blood cancer (Leukaemia)

Cannabinoid Receptor-Mediated Apoptosis Induced by R(+)-Methanandamide and Win55,212-2 Is Associated with Ceramide Accumulation and p38 Activation in Mantle Cell Lymphoma (2006)

Delta9-tetrahydrocannabinol-induced apoptosis in Jurkat leukaemia T cells is regulated by translocation of Bad to mitochondria (2006)

Expression of cannabinoid receptors type 1 and type 2 in non-Hodgkin lymphoma: Growth inhibition by receptor activation (2008)

Oral cancer

Cannabinoids inhibit cellular respiration of human oral cancer cells (2010)

Liver cancer

Anti-tumoral action of cannabinoids on hepatocellular carcinoma: role of AMPK-dependent activation of autophagy (2011)

Pancreatic cancer

Cannabinoids Induce Apoptosis of Pancreatic Tumor Cells via Endoplasmic Reticulum Stress–Related Genes (2006)